Kisspeptin-10 stimulates GnRH neurons upstream in the HPG axis, leading to downstream LH/FSH release. It is studied for reproductive timing, fertility, and puberty-related mechanisms.

Research Focus:

• GnRH/LH/FSH cascade activation
• Fertility and reproductive timing
• HPG-axis diagnostics

Sources:

Landmark GnRH stimulation (PNAS): https://www.pnas.org/doi/10.1073/pnas.0408315102

Human reproductive hormone effects (J Clin Invest): https://www.jci.org/articles/view/26616

Review of kisspeptin physiology (Endocrine Reviews): https://academic.oup.com/edrv/article/28/7/713/2355076

⚠️ Disclaimer: For research use only. Not intended for human consumption. This information is provided for educational purposes and has not been evaluated by the FDA.