MOTS-c is a mitochondrial-derived peptide implicated in metabolic homeostasis, insulin sensitivity, and exercise-like adaptations. Research examines its role in AMPK activation and stress resilience.

Research Focus:

• Metabolic regulation and insulin sensitivity
• Exercise mimetic effects
• Cellular stress adaptation

Sources:

Discovery & metabolic role (Cell Metabolism): https://www.cell.com/cell-metabolism/fulltext/S1550-4131(15)00369-0

Exercise response/mitochondrial signaling (Nature Communications): https://www.nature.com/articles/s41467-015-06743-5

Mitochondrial-derived peptides review (Trends in Endocrinology & Metabolism): https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(16)30003-5

⚠️ Disclaimer: For research use only. Not intended for human consumption. This information is provided for educational purposes and has not been evaluated by the FDA.